Nobel Laureate Quotes

The atom can't be seen, yet its existence can be proved. And it is simple to prove that it can't ever be seen. It has to be studied by indirect evidence — and the technical difficulty has been compared to asking a man who has never seen a piano to describe a piano from the sound it would make falling downstairs in the dark.

Life is not a miracle. It is a natural phenomenon, and can be expected to appear whenever there is a planet whose conditions duplicate those of the

The answer to the ancient question 'Why is there something rather than nothing?' would then be that ‘nothing’ is unstable.

I am an atheist.

To me, science is an expression of the human spirit, which reaches every sphere of human culture. It gives an aim and meaning to existence as well as a knowledge, understanding, love, and admiration for the world. It gives a deeper meaning to morality and another dimension to esthetics.

Individual events. Events beyond law. Events so numerous and so uncoordinated that, flaunting their freedom from formula, they yet fabricate firm form.

The fundamental biological variant is DNA. That is why Mendel's definition of the gene as the unvarying bearer of hereditary traits, its chemical identification by Avery (confirmed by Hershey), and the elucidation by Watson and Crick of the structural basis of its replicative invariance, are without any doubt the most important discoveries ever made in biology. To this must be added the theory of natural selection, whose certainty and full significance were established only by those later theories.

If a problem is clearly stated, it has no further interest to the physicist.

We may fondly imagine that we are impartial seekers after truth, but with a few exceptions, to which I know that I do not belong, we are influenced—and sometimes strongly—by our personal bias; and we give our best thoughts to those ideas which we have to defend.

I studied calculus for the first time, which to me was an amazingly empowering experience which I could really see how you could understand all sorts of things, and I decided that chemistry and biology just had too much memory for me to be interested. Physics was very easy.

I looked for it [heavy hydrogen, deuterium] because I thought it should exist. I didn't know it would have industrial applications or be the basic for the most powerful weapon ever known [the nuclear bomb] ... I thought maybe my discovery might have the practical value of, say, neon in neon s

I cannot understand why we idle discussing religion. If we are honest—and scientists have to be—we must admit that religion is a jumble of false assertions, with no basis in reality. The very idea of God is a product of the human imagination. It is quite understandable why primitive people, who were so much more exposed to the overpowering forces of nature than we are today, should have personified these forces in fear and trembling. But nowadays, when we understand so many natural processes, we have no need for such solutions. I can't for the life of me see how the postulate of an Almighty God helps us in any way. What I do see is that this assumption leads to such unproductive questions as why God allows so much misery and injustice, the exploitation of the poor by the rich and all the other horrors He might have prevented. If religion is still being taught, it is by no means because its ideas still convince us, but simply because some of us want to keep the lower classes quiet. Quiet people are much easier to govern than clamorous and dissatisfied ones. They are also much easier to exploit. Religion is a kind of opium that allows a nation to lull itself into wishful dreams and so forget the injustices that are being perpetrated against the people. Hence the close alliance between those two great political forces, the State and the Church. Both need the illusion that a kindly God rewards—in heaven if not on earth—all those who have not risen up against injustice, who have done their duty quietly and uncomplainingly. That is precisely why the honest assertion that God is a mere product of the human imagination is branded as the worst of all mortal sins.

More than any other product of human scientific culture scientific knowledge is the collective property of all mankind.

It is essential for genetic material to be able to make exact copies of itself; otherwise growth would produce disorder, life could not originate, and favourable forms would not be perpetuated by natural selection.

I might paraphrase Churchill and say: never have I received so much for so little.[Exemplifying humility, upon accepting the Nobel Prize in Chemistry.]

Frederick Douglass told in his Narrative how his condition as a slave became worse when his master underwent a religious conversion that allowed him to justify slavery as the punishment of the children of Ham. Mark Twain described his mother as a genuinely good person, whose soft heart pitied even Satan, but who had no doubt about the legitimacy of slavery, because in years of living in antebellum Missouri she had never heard any sermon opposing slavery, but only countless sermons preaching that slavery was God's will. With or without religion, good people can behave well and bad people can do evil; but for good people to do evil — that takes religion.

One can still say that quantum mechanics is the key to understanding magnetism. When one enters the first room with this key there are unexpected rooms beyond, but it is always the master key that unlocks each door.

I have not yet lost a feeling of wonder, and of delight, that this delicate motion should reside in all the things around us, revealing itself only to him who looks for it. I remember, in the winter of our first experiments, just seven years ago, looking on snow with new eyes. There the snow lay around my doorstep — great heaps of protons quietly precessing in the earth's magnetic field. To see the world for a moment as something rich and strange is the private reward of many a discovery.

Nature seems to take advantage of the simple mathematical representations of the symmetry laws. When one pauses to consider the elegance and the beautiful perfection of the mathematical reasoning involved and contrast it with the complex and far-reaching physical consequences, a deep sense of respect for the power of the symmetry laws never fails to develop.

A DNA sequence for the genome of bacteriophage ΦX174 of approximately 5,375 nucleotides has been determined using the rapid and simple 'plus and minus' method. The sequence identifies many of the features responsible for the production of the proteins of the nine known genes of the organism, including initiation and termination sites for the proteins and RNAs. Two pairs of genes are coded by the same region of DNA using different reading frames.

The future of mankind is going to be decided within the next two generations, and there are two absolute requisites: We must aim at a stable-state society [with limited population growth] and the destruction of nuclear stockpiles. … Otherwise I don't see how we can survive much later than 2050.

I would not be among you to-night (being awarded the 1964 Nobel Prize in Physiology or Medicine) but for the mentors, colleagues and students who have guided and aided me throughout my scientific life. I wish I could name them all and tell you their contributions. More, however, than anyone else it was the late Rudolf Schoenheimer, a brilliant scholar and a man of infectious enthusiasm, who introduced me to the wonders of Biochemistry. Ever since, I have been happy to have chosen science as my career, and, to borrow a phrase of Jacques Barzun, have felt that 'Science is, in the best and strictest sense, glorious entertainment'.

A recognized fact which goes back to the earliest times is that every living organism is not the sum of a multitude of unitary processes, but is, by virtue of interrelationships and of higher and lower levels of control, an unbroken unity. When research, in the efforts of bringing understanding, as a rule examines isolated processes and studies them, these must of necessity be removed from their context. In general, viewed biologically, this experimental separation involves a sacrifice. In fact, quantitative findings of any material and energy changes preserve their full context only through their being seen and understood as parts of a natural order.

From the age of 13, I was attracted to physics and mathematics. My interest in these subjects derived mostly from popular science books that I read avidly. Early on I was fascinated by theoretical physics and determined to become a theoretical physicist. I had no real idea what that meant, but it seemed incredibly exciting to spend one's life attempting to find the secrets of the universe by using one's mind.

In science there is and will remain a Platonic element which could not be taken away without ruining it. Among the infinite diversity of singular phenomena science can only look for invariants.

But every day I go to work I'm making a bet that the universe is simple, symmetric, and aesthetically pleasing—a universe that we humans, with our limited perspective, will someday understand.

I had fallen in love with a young man..., and we were planning to get married. And then he died of subacute bacterial endocarditis... Two years later with the advent of penicillin, he would have been saved. It reinforced in my mind the importance of scientific discovery...

The discovery of an interaction among the four hemes made it obvious that they must be touching, but in science what is obvious is not necessarily true. When the structure of hemoglobin was finally solved, the hemes were found to lie in isolated pockets on the surface of the subunits. Without contact between them how could one of them sense whether the others had combined with oxygen? And how could as heterogeneous a collection of chemical agents as protons, chloride ions, carbon dioxide, and diphosphoglycerate influence the oxygen equilibrium curve in a similar way? It did not seem plausible that any of them could bind directly to the hemes or that all of them could bind at any other common site, although there again it turned out we were wrong. To add to the mystery, none of these agents affected the oxygen equilibrium of myoglobin or of isolated subunits of hemoglobin. We now know that all the cooperative effects disappear if the hemoglobin molecule is merely split in half, but this vital clue was missed. Like Agatha Christie, Nature kept it to the last to make the story more exciting. There are two ways out of an impasse in science: to experiment or to think. By temperament, perhaps, I experimented, whereas Jacques Monod thought.

Unless social sciences can be as creative as natural science, our new tools are not likely to be of much use to us.

Nature creates curved lines while humans create straight lines.

...the scientific attitude implies what I call the postulate of objectivity—that is to say, the fundamental postulate that there is no plan, that there is no intention in the universe. Now, this is basically incompatible with virtually all the religious or metaphysical systems whatever, all of which try to show that there is some sort of harmony between man and the universe and that man is a product—predictable if not indispensable—of the evolution of the universe.

Discovery consists of looking at the same thing as everyone else and thinking something different.

I am not religious in any sense; in fact, I consider myself an atheist.

Any chemist reading this book can see, in some detail, how I have spent most of my mature life. They can become familiar with the quality of my mind and imagination. They can make judgements about my research abilities. They can tell how well I have documented my claims of experimental results. Any scientist can redo my experiments to see if they still work—and this has happened! I know of no other field in which contributions to world culture are so clearly on exhibit, so cumulative, and so subject to verification.

It has been demonstrated that a species of penicillium produces in culture a very powerful antibacterial substance which affects different bacteria in different degrees. Generally speaking it may be said that the least sensitive bacteria are the Gram-negative bacilli, and the most susceptible are the pyogenic cocci ... In addition to its possible use in the treatment of bacterial infections penicillin is certainly useful... for its power of inhibiting unwanted microbes in bacterial cultures so that penicillin insensitive bacteria can readily be isolated.

I think that the event which, more than anything else, led me to the search for ways of making more powerful radio telescopes, was the recognition, in 1952, that the intense source in the constellation of Cygnus was a distant galaxy—1000 million light years away. This discovery showed that some galaxies were capable of producing radio emission about a million times more intense than that from our own Galaxy or the Andromeda nebula, and the mechanisms responsible were quite unknown. ... [T]he possibilities were so exciting even in 1952 that my colleagues and I set about the task of designing instruments capable of extending the observations to weaker and weaker sources, and of exploring their internal structure.

[In the case of research director, Willis R. Whitney, whose style was to give talented investigators as much freedom as possible, you may define 'serendipity' as] the art of profiting from unexpected occurrences. When you do things in that way you get unexpected results. Then you do something else and you get unexpected results in another line, and you do that on a third line and then all of a sudden you see that one of these lines has something to do with the other. Then you make a discovery that you never could have made by going on a direct road.

My laboratory is interested in the related challenges of understanding the origin of life on the early earth, and constructing synthetic cellular life in the laboratory. Focusing on artificial life frees us to explore novel chemical systems, but what we learn from these systems helps us to understand possible pathways leading to the origin of life. Our basic design for a synthetic cell involves the encapsulation of a spontaneously replicating nucleic acid, which acts as the genetic material, within a spontaneously replicating membrane vesicle, which provides spatial localization. We are using chemical synthesis to make nucleic acids with modified nucleobases and sugar-phosphate backbones.

We live in a world where unfortunately the distinction between true and false appears to become increasingly blurred by manipulation of facts, by exploitation of uncritical minds, and by the pollution of the language.

The literature [Nobel] laureate of this year has said that an author can do anything as long as his readers believe him.A scientist cannot do anything that is not checked and rechecked by scientists of this network before it is accepted.

It was quite the most incredible event that has ever happened to me in my life. It was almost as incredible as if you fired a 15-inch shell at a piece of tissue paper and it came back and hi

During this time (at high school) I discovered the Public Library... It was here that I found a source of knowledge and the means to acquire it by reading, a habit of learning which I still follow to this day. I also became interested in chemistry and gradually accumulated enough test tubes and other glassware to do chemical experiments, using small quantities of chemicals purchased from a pharmacy supply house. I soon graduated to biochemistry and tried to discover what gave flowers their distinctive colours. I made the (to me) astounding discovery that the pigments I extracted changed their colours when I changed the pH of the solution.

Emil Fischer represents a symbol of Germany's greatness.

Should the research worker of the future discover some means of releasing this [atomic] energy in a form which could be employed, the human race will have at its command powers beyond the dream of scientific fiction, but the remotest possibility must always be considered that the energy once liberated will be completely uncontrollable and by its intense violence detonate all neighbouring substances. In this event, the whole of the hydrogen on earth might be transformed at once and the success of the experiment published at large to the universe as a new star.

I should like to preface my remarks with a personal statement in order that my later remarks will not be misunderstood. I consider myself an atheist.

I have a friend — or had a friend, now dead — Abdus Salam, a very devout Muslim, who was trying to bring science into the universities in the Gulf states and he told me that he had a terrible time because, although they were very receptive to technology, they felt that science would be a corrosive to religious belief, and they were worried about it… and damn it, I think they were right. It is corrosive of religious belief, and it’s a good thing too.

I have no doubt that we will be successful in harnessing the sun's energy. ... If sunbeams were weapons of war, we would have had solar energy centuries ago.

Dreaming is the poetry of Life, and we must be forgiven if we indulge in it a little.

True, the initial ideas are in general those of an individual, but the establishment of the reality and truth is in general the work of more than one person.

Littlewood, on Hardy's own estimate, is the finest mathematician he has ever known. He was the man most likely to storm and smash a really deep and formidable problem; there was no one else who could command such a combination of insight, technique and power.

If the militarily most powerful and least threatened states need nuclear weapons for their security, how can one deny such security to countries that are truly insecure? The present nuclear policy is a recipe for proliferation. It is a policy for disaster.

Now I know what the atom looks like.

It would be pleasant to believe that the age of pessimism is now coming to a close, and that its end is marked by the same author who marked its beginning: Aldous Huxley. After thirty years of trying to find salvation in mysticism, and assimilating the Wisdom of the East, Huxley published in 1962 a new constructive utopia, The Island. In this beautiful book he created a grand synthesis between the science of the West and the Wisdom of the East, with the same exceptional intellectual power which he displayed in his Brave New World. (His gaminerie is also unimpaired; his close union of eschatology and scatology will not be to everybody's tastes.) But though his Utopia is constructive, it is not optimistic; in the end his island Utopia is destroyed by the sort of adolescent gangster nationalism which he knows so well, and describes only too convincingly.This, in a nutshell, is the history of thought about the future since Victorian days. To sum up the situation, the sceptics and the pessimists have taken man into account as a whole; the optimists only as a producer and consumer of goods. The means of destruction have developed pari passu with the technology of production, while creative imagination has not kept pace with either.The creative imagination I am talking of works on two levels. The first is the level of social engineering, the second is the level of vision. In my view both have lagged behind technology, especially in the highly advanced Western countries, and both constitute dangers.

The history of atomism is one of reductionism – the effort to reduce all the operations of nature to a small number of laws governing a small number of primordial objects.

The field of scientific abstraction encompasses independent kingdoms of ideas and of experiments and within these, rulers whose fame outlasts the centuries. But they are not the only kings in science. He also is a king who guides the spirit of his contemporaries by knowledge and creative work, by teaching and research in the field of applied science, and who conquers for science provinces which have only been raided by craftsmen.

I told my three sons stories about germs more than fifty years ago as fanciful bedtime tales.

Scientific truth is universal, because it is only discovered by the human brain and not made by it, as art is.

Tapestries are made by many artisans working together. The contributions of separate workers cannot be discerned in the completed work, and the loose and false threads have been covered over. So it is in our picture of particle physics.

If my efforts have led to greater success than usual, this is due, I believe, to the fact that during my wanderings in the field of medicine, I have strayed onto paths where the gold was still lying by the wayside. It takes a little luck to be able to distinguish gold from dross, but that is all.

Lastly, and doubtless always, but particularly at the end of the last century, certain scholars considered that since the appearances on our scale were finally the only important ones for us, there was no point in seeking what might exist in an inaccessible domain. I find it very difficult to understand this point of view since what is inaccessible today may become accessible tomorrow (as has happened by the invention of the microscope), and also because coherent assumptions on what is still invisible may increase our understanding of the visible.